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NRAS (p.G12D)

Variant Data

Location

  • HGVS: ENST00000369535:c.35G>A
  • Reference Version: GRCh37
  • Chromosome: 1
  • Start: 115258747
  • Stop: 115258747
  • Strand: -1
  • Transcript: ENST00000369535 (ensembl - 74_37)
  • Gene: NRAS ( View drug interactions on DGIdb )

Information

Disease Data

Disease Source Batch Tags External Links
melanoma van 't Veer et al., 1989, Mol. Cell. Biol. My Cancer Genome (View variants) pathogenic My Cancer Genome
melanoma Ball et al., 1994, J. Invest. Dermatol. My Cancer Genome (View variants) pathogenic My Cancer Genome
non-small cell lung carcinoma Brose et al., 2002, Cancer Res. My Cancer Genome (View variants) pathogenic My Cancer Genome
colorectal cancer Solit et al., 2006, Nature My Cancer Genome (View variants) pathogenic My Cancer Genome
melanoma Curtin et al., 2005, N. Engl. J. Med. My Cancer Genome (View variants) pathogenic My Cancer Genome
colorectal cancer Davies et al., 2007, Mol. Cancer Ther. My Cancer Genome (View variants) pathogenic My Cancer Genome
melanoma Adjei et al., 2008, J. Clin. Oncol. My Cancer Genome (View variants) pathogenic My Cancer Genome
non-small cell lung carcinoma Ding et al., 2008, Nature My Cancer Genome (View variants) pathogenic My Cancer Genome
melanoma Hatzivassiliou et al., 2010, Nature My Cancer Genome (View variants) pathogenic My Cancer Genome
melanoma Poulikakos et al., 2010, Nature My Cancer Genome (View variants) pathogenic My Cancer Genome
colorectal cancer De Roock et al., 2010, Lancet Oncol. My Cancer Genome (View variants) pathogenic My Cancer Genome
colorectal cancer Irahara et al., 2010, Diagn. Mol. Pathol. My Cancer Genome (View variants) pathogenic My Cancer Genome
colorectal cancer Vaughn et al., 2011, Genes Chromosomes Cancer My Cancer Genome (View variants) pathogenic My Cancer Genome
colorectal cancer De Mattos-Arruda et al., 2011, Clin Colorectal Cancer My Cancer Genome (View variants) pathogenic My Cancer Genome
colorectal cancer Janku et al., 2011, PLoS ONE My Cancer Genome (View variants) pathogenic My Cancer Genome
melanoma Ascierto et al., 2013, Lancet Oncol. My Cancer Genome (View variants) pathogenic My Cancer Genome
non-small cell lung carcinoma Ohashi et al., 2013, Clin. Cancer Res. My Cancer Genome (View variants) pathogenic My Cancer Genome
acute myeloid leukemia Vogelstein et al., 1990, Genes Chromosomes Cancer WashU hematologic malignancy mutation list (View variants) likely pathogenic
acute myeloid leukemia Janssen et al., 1987, Proc. Natl. Acad. Sci. U.S.A. WashU hematologic malignancy mutation list (View variants) likely pathogenic
acute myeloid leukemia Bacher et al., 2006, Blood WashU hematologic malignancy mutation list (View variants) likely pathogenic
acute myeloid leukemia Tyner et al., 2009, Blood WashU hematologic malignancy mutation list (View variants) likely pathogenic
acute myeloid leukemia Mardis et al., 2009, N. Engl. J. Med. WashU hematologic malignancy mutation list (View variants) likely pathogenic
acute myeloid leukemia Xu et al., 2012, Blood WashU hematologic malignancy mutation list (View variants) likely pathogenic
acute myeloid leukemia Sano et al., 2012, Int. J. Hematol. WashU hematologic malignancy mutation list (View variants) likely pathogenic
acute myeloid leukemia MacConaill et al., 2014, J Mol Diagn WashU hematologic malignancy mutation list (View variants) likely pathogenic
colorectal cancer Chang et al., 2016, Nat. Biotechnol. Pan-cancer recurrent hotspots (View variants) likely pathogenic
skin melanoma Chang et al., 2016, Nat. Biotechnol. Pan-cancer recurrent hotspots (View variants) likely pathogenic
acute myeloid leukemia Chang et al., 2016, Nat. Biotechnol. Pan-cancer recurrent hotspots (View variants) likely pathogenic
multiple myeloma Chang et al., 2016, Nat. Biotechnol. Pan-cancer recurrent hotspots (View variants) likely pathogenic
uterine corpus endometrial carcinoma Chang et al., 2016, Nat. Biotechnol. Pan-cancer recurrent hotspots (View variants) likely pathogenic
myelodysplastic syndrome Chang et al., 2016, Nat. Biotechnol. Pan-cancer recurrent hotspots (View variants) likely pathogenic
gastric adenocarcinoma Chang et al., 2016, Nat. Biotechnol. Pan-cancer recurrent hotspots (View variants) likely pathogenic
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